Overview

  • Product nameRecombinant Human Tau383 protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • Amino acids1 to 383

Specifications

Our Abpromise guarantee covers the use of ab84766 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5

General Info

  • Alternative names
    • AI413597
    • AW045860
    • DDPAC
    • FLJ31424
    • FTDP 17
    • G protein beta1/gamma2 subunit-interacting factor 1
    • MAPTL
    • MGC138549
    • MGC156663
    • Microtubule associated protein tau
    • Microtubule associated protein tau, isoform 4
    • MSTD
    • Mtapt
    • MTBT1
    • MTBT2
    • Neurofibrillary tangle protein
    • OTTMUSP00000003078
    • OTTMUSP00000003083
    • Paired helical filament-tau
    • PHF tau
    • PPND
    • pTau
    • rCG_32645
    • RNPTAU
    • RP23-136D4.1
    • TAU
    • Tau D
    see all
  • RelevanceTau383 is a memeber of the family of neuronal microtubule-associated proteins. Tau promotes assembly and stabilizes neuronal microtubules under normal physiological conditions, but under pathological conditions can also undergo modifications such as hyperphosphorylation, that can result in the generation of aberrant aggregates such as found in neurofibrillary tangles in Alzheimer's disease. Six isoforms have been found that differ from each other in having either 3 or 4 binding repeats (R) of 31-32 amino acids, and from zero to 3 amino terminal inserts (N) of 29 amino acids each.
  • Cellular localizationCytoplasm; cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm; cytoskeleton. Cell projection; axon. Note: Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components

Recombinant Human Tau383 protein images

  • SDS-PAGE showing ab84766 at approximately 52kDa.

References for Recombinant Human Tau383 protein (ab84766)

ab84766 has not yet been referenced specifically in any publications.

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