Recombinant Human TCEAL1 protein (ab108377)

Overview

  • Product name
    Recombinant Human TCEAL1 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MDKPRKENEEEPQSAPKTDEERPPVEHSPEKQSPEEQSSEEQSSEEEFFP EELLPELLPEMLLSEERPPQEGLSRKDLFEGRPPMEQPPCGVGKHKLEEG SFKERLARSRPQFRGDIHGRNLSNEEMIQAADELEEMKRVRNKLMIMHWK AKRSRPYPILEHHHHHH
    • Molecular weight
      20 kDa including tags
    • Amino acids
      1 to 159
    • Tags
      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab108377 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 90 % SDS-PAGE.
    ab108377 was purified using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 2mM DTT, pH 8.0

General Info

  • Alternative names
    • Highly similar to gene pp21 protein [H.sapiens]
    • Nuclear phosphoprotein p21/SIIR
    • p21
    • pp21
    • SIIR
    • TCAL1_HUMAN
    • TCEA like protein 1
    • TCEA-like protein 1
    • TCEAL1
    • Transcription elongation factor A (SII) like 1
    • Transcription elongation factor A protein like 1
    • Transcription elongation factor A protein-like 1
    • Transcription elongation factor S II protein like 1
    • Transcription elongation factor S-II protein-like 1
    see all
  • Function
    May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly.
  • Tissue specificity
    Expressed in all tissues examined. Highly expressed in heart, ovary, prostate and skeletal muscle. Moderately expressed in brain, placenta, testis and small intestine. Weakly expressed in lung, liver and spleen. Expressed in several cancer cell lines.
  • Sequence similarities
    Belongs to the TFS-II family. TFA subfamily.
  • Post-translational
    modifications
    Phosphorylation of Ser-36 and Ser-37 is critical for transcriptional repression.
  • Cellular localization
    Nucleus.
  • Information by UniProt

Recombinant Human TCEAL1 protein images

  • 15% SDS-PAGE analysis of ab108377 (3µg)

References for Recombinant Human TCEAL1 protein (ab108377)

ab108377 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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