Recombinant human TCPTP protein (Catalytic domain) (ab187235)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSRRAS VMPTTIEREF EELDTQRRWQ PLYLEIRNES HDYPHRVAKF PENRNRNRYR DVSPYDHSRV KLQNAENDYI NASLVDIEEA QRSYILTQGP LPNTCCHFWL MVWQQKTKAV VMLNRIVEKE SVKCAQYWPT DDQEMLFKET GFSVKLLSED VKSYYTVHLL QLENINSGET RTISHFHYTT WPDFGVPESP ASFLNFLFKV RESGSLNPDH GPAVIHCSAG IGRSGTFSLV DTCLVLMEKG DDINIKQVLL NMRKYRMGLI QTPDQLRFSY MAIIEGAKCI KGDSSIQKRW KELSKEDLSP AFDHSPNKIM TEKYNGNRIG LEEEKLTGDR CTGLSSKMQD TMEENSESAL RKRIR
    • Molecular weight
      68 kDa including tags
    • Amino acids
      1 to 354
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab187235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    • Diluting ab187235 1/5200 in assay buffer will give a rate of 25 Fluorescence Units/min at pH 7.0 RT using 50M DIFMUP as substrate.
    • Diluting ab187235 1/200 in assay buffer will give a rate of 0.03 OD/min at pH 7.0 RT using 5mM pNPP as substrate.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity
    >90% by SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.595% HEPES, 0.096% Tris, 50% Glycerol, 0.092% DTT, 0.005% Glutathione, 0.002% EDTA

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Protein tyrosine phosphatase non receptor type 2
    • PTN2
    • PTN2_HUMAN
    • PTPN 2
    • Ptpn2
    • PTPT
    • T cell protein tyrosine phosphatase
    • T-cell protein-tyrosine phosphatase
    • TC PTP
    • TCELLPTP
    • TCPTP
    • Tyrosine protein phosphatase non receptor type 2
    • Tyrosine-protein phosphatase non-receptor type 2
    see all
  • Tissue specificity
    Isoform PTPA is probably the major isoform. Isoform PTPB is expressed in T-cells and in placenta.
  • Sequence similarities
    Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localization
    Cytoplasm; Nucleus and Endoplasmic reticulum.
  • Information by UniProt

References

ab187235 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab187235.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up