The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 µg/µl.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Related to TEF 1
Related to TEF1
Related transcription enhancer factor 1B
TEA domain family member 4
Transcription factor 13 (SV40 transcriptional enhancer factor) like 1
Transcription factor 13 like 1
Transcription factor 13-like 1
Transcription factor RTEF 1
Transcription factor RTEF-1
Transcription factor RTEF1
Transcriptional enhancer factor 1 related
Transcriptional enhancer factor 3
Transcriptional enhancer factor TEF 3
Transcriptional enhancer factor TEF-3
Transcriptional enhancer factor TEF3
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.
Preferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart.