Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      hTECK is a 14.2 kDa protein containing 127 amino acid residues: QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNP KSREVQRAMKLLDAR NKVFAKLHHN MQTFQAGPHA VKKLSSGNSK L SSSKFSNPI SSSRKNVSLLISANSGL

Associated products

Specifications

Our Abpromise guarantee covers the use of ab586 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Endotoxin level
    < 0.100 Eu/µg
  • Form
    Lyophilised
  • Additional notes
    The biological activity of this product is determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ng/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Constituent: 0.06% Acetic acid

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • A130072A22Rik
    • C-C motif chemokine 25
    • CCL 25
    • CCL25
    • CCL25_HUMAN
    • Chemokine (C C motif) ligand 25
    • Chemokine (CC motif) ligand 25
    • Chemokine C C motif ligand 25
    • Chemokine CC motif ligand 25
    • Chemokine TECK
    • Ck beta 15
    • Ckb 15
    • Ckb15
    • MGC125074
    • MGC150327
    • SCY A25
    • SCYA 25
    • SCYA25
    • Small inducible cytokine A25
    • Small inducible cytokine A25 isoform 1 precursor
    • Small inducible cytokine A25 isoform 2 precursor
    • Small inducible cytokine subfamily A (Cys Cys) member 25
    • Small inducible cytokine subfamily A Cys Cys member 25
    • Small inducible cytokine subfamily A, member 25
    • Small-inducible cytokine A25
    • TECK
    • TECKvar
    • Thymus expressed chemokine
    • Thymus-expressed chemokine
    see all
  • Function
    Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1.
  • Tissue specificity
    Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
  • Sequence similarities
    Belongs to the intercrine beta (chemokine CC) family.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab586 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab586.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up