The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
5' TG 3' interacting factor 2
5''-TG-3''-interacting factor 2
Homeobox protein TGIF2
TGF (beta) induced transcription factor 2
TGF-beta-induced transcription factor 2
TGFB induced factor 2
TGFB-induced factor 2
Transforming growth factor beta induced factor 2
Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins.
Widely expressed. Highly expressed in heart, kidney and testis. Weakly expressed in brain and prostate.
Belongs to the TALE/TGIF homeobox family. Contains 1 homeobox DNA-binding domain.
The C-terminal part is phosphorylated in response to EGF signaling by the Ras/MAPK pathway.