Recombinant Human Thymosin beta 4 protein (ab112365)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
    • Molecular weight
      31 kDa including tags
    • Amino acids
      1 to 44
    • Tags
      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab112365 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    ELISA

    Western blot

    Other

  • Form
    Liquid
  • Additional notes
    Best to use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Fx
    • Hematopoietic system regulatory peptide
    • Prothymosin beta 4
    • PTMB 4
    • PTMB4
    • Seraspenide
    • T beta 4
    • T beta-4
    • TB4X
    • THYB 4
    • Thyb4
    • Thymosin beta 4
    • Thymosin beta 4 X chromosome
    • Thymosin beta 4 X linked
    • TMSB 4
    • TMSB4
    • Tmsb4x
    • TYB4_HUMAN
    see all
  • Function
    Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
    Seraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase.
  • Tissue specificity
    Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells.
  • Sequence similarities
    Belongs to the thymosin beta family.
  • Cellular localization
    Cytoplasm > cytoskeleton.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE showing ab112365 at approximately 30.84 kDa, stained with Coomassie Blue.

References

ab112365 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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