Recombinant Human Thymosin beta 4 protein (ab112365)

Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionP62328
    • SpeciesHuman
    • SequenceMSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
    • Molecular weight31 kDa including tags
    • Amino acids1 to 44
    • TagsGST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab112365 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    ELISA

    Western blot

    Other

  • FormLiquid
  • Additional notesBest to use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Fx
    • Hematopoietic system regulatory peptide
    • Prothymosin beta 4
    • PTMB 4
    • PTMB4
    • Seraspenide
    • T beta 4
    • T beta-4
    • TB4X
    • THYB 4
    • Thyb4
    • Thymosin beta 4
    • Thymosin beta 4 X chromosome
    • Thymosin beta 4 X linked
    • TMSB 4
    • TMSB4
    • Tmsb4x
    • TYB4_HUMAN
    see all
  • FunctionPlays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
    Seraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase.
  • Tissue specificityExpressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells.
  • Sequence similaritiesBelongs to the thymosin beta family.
  • Cellular localizationCytoplasm > cytoskeleton.
  • Information by UniProt

Recombinant Human Thymosin beta 4 protein images

  • 12.5% SDS-PAGE showing ab112365 at approximately 30.84 kDa, stained with Coomassie Blue.

References for Recombinant Human Thymosin beta 4 protein (ab112365)

ab112365 has not yet been referenced specifically in any publications.

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