The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. ab73870 is purified by proprietary chromatographic techniques.
Purity is greater than 90.0% as determined by RP-HPLC and SDS-PAGE.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituents: 10% Sucrose, 0.5M Sodium chloride, 20mM Tris
Reconstitute in sterile water not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Upon reconstitution ab73870 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor Homology Domains
Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1
Tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Tyrosine protein kinase receptor Tie 1
Tyrosine-protein kinase receptor Tie-1
Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.
Specifically expressed in developing vascular endothelial cells.
Belongs to the protein kinase superfamily. Tyr protein kinase family. Tie subfamily. Contains 3 EGF-like domains. Contains 3 fibronectin type-III domains. Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 protein kinase domain.
Phosphorylated on tyrosine residues in response to ANGPT1, most likely by TEK/TIE2.