Overview

  • Product nameRecombinant Human TIFA protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionQ96CG3
    • SpeciesHuman
    • SequenceMGSSHHHHHH SSGLVPRGSH MGSHMTSFED ADTEETVTCL QMTVYHPGQL QCGIFQSISF NREKLPSSEV VKFGRNSNIC HYTFQDKQVS RVQFSLQLFK KFNSSVLSFE IKNMSKKTNL IVDSRELGYL NKMDLPYRCM VRFGEYQFLM EKEDGESLEF FETQFILSPR SLLQENNWPP HRPIPEYGTY SLCSSQSSSP TEMDENES
    • Molecular weight24 kDa including tags
    • Amino acids1 to 184
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab123199 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity> 90 % SDS-PAGE.
    ab123199 is purified using conventional chromatography techniques.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol

General Info

  • Alternative names
    • Putative MAPK activating protein PM14
    • Putative MAPK-activating protein PM14
    • Putative NF kappa B activating protein 20
    • Putative NF-kappa-B-activating protein 20
    • T2BP
    • TIFA
    • TIFA_HUMAN
    • TRAF interacting protein with FHA domain containing protein A
    • TRAF-interacting protein with FHA domain-containing protein A
    • TRAF2 binding protein
    • TRAF2-binding protein
    see all
  • FunctionAdapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.
  • Sequence similaritiesContains 1 FHA domain.
  • Information by UniProt

Recombinant Human TIFA protein images

  • 15% SDS-PAGE showing ab123199 (3µg).

References for Recombinant Human TIFA protein (ab123199)

ab123199 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"