Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMGSHMARFALTVVRHGETRFNKEKIIQGQG VDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMRTKQTMHGILERSKFC KDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPGGETLD QVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNH SSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSEL MSVTPNTGMSLFIINFEEGREVKPTVQCICMNLQDHLNGLTETR
    • Molecular weight
      33 kDa including tags
    • Amino acids
      1 to 270
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab101635 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 90 % SDS-PAGE.
    ab101635 was purified using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 0.2M Sodium chloride, 20mM Tris HCl, 2mM DTT, pH 8.0

General Info

  • Alternative names
    • 6-bisphosphatase TIGAR
    • C12ORF5
    • chromosome 12 open reading frame 5
    • FR2BP
    • Fructose-2,6-bisphosphatase TIGAR
    • Fructose-2,6-bisphosphate 2-phosphatase
    • Probable fructose 2,6 bisphosphatase TIGAR
    • Probable fructose-2
    • tigar
    • TIGAR_HUMAN
    • TP53 induced glycolysis and apoptosis regulator
    • TP53 induced glycolysis regulatory phosphatase
    • TP53-induced glycolysis and apoptosis regulator
    • Transactivated by NS3TP2 protein
    see all
  • Function
    Probable fructose-biphosphatase. Lowers cellular levels of fructose 2,6-bisphosphate. Protects cells against reactive oxygen species and against apoptosis induced by p53/TP53.
  • Sequence similarities
    Belongs to the phosphoglycerate mutase family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of 3 µg ab101635.

References

ab101635 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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