Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 µg/ml.
Dissolve the lyophilized protein in 1X PBS.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Collagenase inhibitor, Human
Erythroid Potentiating Activity
Fibroblast collagenase inhibitor
Human Collagenase Inhibitor
Metalloproteinase inhibitor 1
Metalloproteinase inhibitor 1 precursor
TIMP metallopeptidase inhibitor 1
Tissue Inhibitor of Metalloproteinase 1
Tissue inhibitor of metalloproteinases
Tissue inhibitor of metalloproteinases 1
Ttissue inhibitor of metalloproteinase 1 erythroid potentiating activity collagenase inhibitor
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14.
Belongs to the protease inhibitor I35 (TIMP) family. Contains 1 NTR domain.
The activity of TIMP1 is dependent on the presence of disulfide bonds.