The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityHomologous to the extracellular domain of Human TNF18, Thr53-Ser177.
Additional notesLyophilized product although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution the product should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.Homologous to the extracellular domain of Human TNF18, Thr53-Ser177.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
ReconstitutionLyophilized from 0.5 mg/ml in 0.03M Acetate buffer, pH 4.
Add 0.2 ml of 0.1M Acetate buffer pH 4 and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10µg/ml. In higher concentrations the solubility of this antigen is limited.
Activation inducible TNF related ligand
Activation-inducible TNF-related ligand
Glucocorticoid induced TNF related ligand
Glucocorticoid induced TNFR related protein ligand
Glucocorticoid-induced TNF-related ligand
Tumor necrosis factor (ligand) superfamily member 18
Tumor necrosis factor ligand 2A
Tumor necrosis factor ligand superfamily member 18
FunctionCytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues.
Tissue specificityExpressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.
Sequence similaritiesBelongs to the tumor necrosis factor family.