Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab73786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.
    ab73786 is purified by proprietary chromatographic techniques. Purity is greater than 90.0% as determined by RP-HPLC and SDS-PAGE.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 6M Urea, 500mM Sodium chloride, 10mM Tris, pH 8.0

General Info

  • Alternative names
    • 60 kDa ribonucleoprotein Ro
    • 60 kDa Ro protein
    • 60 kDa SS A/Ro ribonucleoprotein
    • 60 kDa SS-A/Ro ribonucleoprotein
    • Autoantigen Ro/SSA, 60-KD
    • bA101E13.2
    • Gastric cancer multi drug resistance protein
    • Ribonucleoprotein autoantigen SS A/Ro
    • RO 60
    • Ro 60 kDa autoantigen
    • RO60
    • RO60_HUMAN
    • RoRNP
    • Sjoegren syndrome antigen A2
    • Sjoegren syndrome type A antigen
    • Sjogren syndrome antigen A2
    • Sjogren syndrome antigen A2 (60kD ribonucleoprotein autoantigen SS A/Ro)
    • Sjogren syndrome antigen A2 (60kDa ribonucleoprotein autoantigen SS A/Ro)
    • SS A
    • SS-A
    • SS-A/Ro
    • SSA
    • SSA 2
    • SSA2
    • TROVE 2
    • TROVE domain family member 2
    • TROVE2
    see all
  • Function
    RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation.
  • Sequence similarities
    Belongs to the Ro 60 kDa family.
    Contains 1 TROVE domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Information by UniProt

References

ab73786 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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