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Amino Acid Sequence
Sequence MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPA DFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLE LIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNI KLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIW SLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIY HMLQPDVNRRLHIDEILSHCWMQPKARGSPSVAINKEGESSRGTEPLWTP EPGSDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPST METEEGPPQQPPETRAQ
Molecular weight 71 kDa including tags
Amino acids 1 to 367 Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activity The specific activity of TSSK1 was determined to be 60 nmol/min/mg.
Purity > 80
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
This product is an active protein and may elicit a biological response in vivo, handle with caution.
serine/threonine kinase 22D (spermiogenesis associated)
serine/threonine kinase FKSG81
Function Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-288' of TSKS. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.
Tissue specificity Testis-specific. Present in sperm (at protein level).
Sequence similarities Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Contains 1 protein kinase domain.
Post-translational modifications Autophosphorylated.
Cellular localization Cytoplasm. Cytoplasmic vesicle > secretory vesicle > acrosome. Cell projection > cilium > flagellum. In spermatozoa, present in the sperm head and in the flagellum.
Information by UniProt
Recombinant human TSSK1 protein images
SDS-PAGE - TSSK1 protein (ab101710)
The putity of ab101710 was determined to be 80% by SDS-PAGE
Approximate MWt: 71kDa
Functional Studies - TSSK1 protein (ab101710)
Sample Kinase Activity Plot for TSSK1 (ab101710). The specific activity of ab101710 was determined to be 60 nmol/min/mg.
References for Recombinant human TSSK1 protein (ab101710)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"