Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MEAVLNELVS VEDLLKFEKK FQSEKAAGSV SKSTQFEYAW CLVRSKYNDD IRKGIVLLEE LLPKGSKEEQ RDYVFYLAVG NYRLKEYEKA LKYVRGLLQT EPQNNQAKEL ERLIDKAMKK DG
    • Molecular weight
      16 kDa including tags
    • Amino acids
      1 to 122
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab95499 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Purity
    > 95 % SDS-PAGE.
    ab95499 is purified using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, pH 8.0

General Info

  • Alternative names
    • 2010003O14Rik
    • CGI 135
    • CGI135
    • FIS 1
    • FIS1
    • Fis1 homolog
    • FIS1, S. cerevisiae, homolog of
    • FIS1_HUMAN
    • Fission 1 (mitochondrial outer membrane) homolog
    • Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
    • Fission 1 (mitochondrial outer membrane) homolog (yeast)
    • Fission 1 homolog
    • H NH0132A01.6
    • hFis 1
    • hFis1
    • Mitochondrial fission 1 protein
    • mitochondrial fission molecule
    • Tetratricopeptide repeat domain 11
    • Tetratricopeptide repeat protein 11
    • TPR repeat protein 11
    • TTC 11
    see all
  • Function
    Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
  • Sequence similarities
    Belongs to the FIS1 family.
    Contains 1 TPR repeat.
  • Domain
    The C-terminus is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.
  • Post-translational
    modifications
    Ubiquitinated by MARCH5.
  • Cellular localization
    Mitochondrion outer membrane. Peroxisome membrane.
  • Information by UniProt

Recombinant Human TTC11 protein images

  • 15% SDS-PAGE showing ab95499 at approximately 16.3kDa (3µg).

References for Recombinant Human TTC11 protein (ab95499)

ab95499 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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