Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGSMAAPAGG GGSAVSVLAP NGRRHTVKVT PSTVLLQVLE DTCRRQDFNP CEYDLKFQRS VLDLSLQWRF ANLPNNAKLE MVPASRSREG PENMVRIALQ LDDGSRLQDS FCSGQTLWEL LSHFPQIREC LQHPGGATPV CVYTRDEVTG EAALRGTTLQ SLGLTGGSAT IRFVMKCYDP VGKTPGSLGS SASAGQAAAS APLPLESGEL SRGDLSRPED ADTSGPCCEH TQEKQSTRAP AAAPFVPFSG GGQRLGGPPG PTRPLTSSSA KLPKSLSSPG GPSKPKKSKS GQDPQQEQEQ ERERDPQQEQ ERERPVDREP VDREPVVCHP DLEERLQAWP AELPDEFFEL TVDDVRRRLA QLKSERKRLE EAPLVTKAFR EAQIKEKLER YPKVALRVLF PDRYVLQGFF RPSETVGDLR DFVRSHLGNP ELSFYLFITP PKTVLDDHTQ TLFQANLFPA ALVHLGAEEP AGVYLEPGLL EHAISPSAAD VLVARYMSRA AGSPSPLPAP DPAPKSEPAA EEGALVPPEP IPGTAQPVKR SLGKVPKWLK LPASKR
    • Molecular weight
      63 kDa including tags
    • Amino acids
      1 to 553
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab167886 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 85 % SDS-PAGE.
    ab167886 is purified using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.88% Sodium chloride

General Info

  • Alternative names
    • Alveolar soft part sarcoma chromosomal region candidate gene 1 protein
    • Alveolar soft part sarcoma chromosome region candidate 1 (human)
    • Alveolar soft part sarcoma locus
    • ASPC
    • ASPC1_HUMAN
    • ASPCR 1
    • ASPCR1
    • ASPL
    • ASPS
    • ASPSCR 1
    • Aspscr1
    • FLJ45380
    • RCC 17
    • RCC17
    • renal cell carcinoma gene on chromosome 17
    • renal cell carcinoma papillary 17
    • Renal papillary cell carcinoma protein 17
    • Tether containing a UBX domain for GLUT4
    • Tether containing UBX domain for GLUT4
    • TUG
    • UBX domain containing protein 9
    • UBX domain protein 9
    • UBX domain-containing protein 9
    • UBXD 9
    • UBXD9
    • UBXN 9
    • UBXN9
    see all
  • Function
    Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface.
  • Tissue specificity
    Ubiquitous. Highly expressed in testis, heart, skeletal muscle and pancreas.
  • Involvement in disease
    Note=A chromosomal aberration involving ASPSCR1 is found in patients with alveolar soft part sarcoma. Translocation t(X;17)(p11;q25) with TFE3 forms a ASPSCR1-TFE3 fusion protein.
    Note=A chromosomal aberration involving ASPSCR1 has been found in two patients with of papillary renal cell carcinoma. Translocation t(X;17)(p11.2;q25).
  • Sequence similarities
    Contains 1 UBX domain.
  • Cellular localization
    Endomembrane system.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab167886 (3µg).

References

ab167886 has not yet been referenced specifically in any publications.

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