For the best experience on the Abcam website please upgrade to a modern browser such as
Source Escherichia coli
Amino Acid Sequence
Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWAGSMEI TSLDTENIDE ILNNADVALV NFYADWCRFS QMLHPIFEEA SDVIKEEFPNENQVVFARVD CDQHSDIAQR YRISKYPTLK LFRNGMMMKR EYRGQRSVKA LADYIRQQKS DPIQEIRDLA EITTLDRSKR NIIGYFEQKDSDNYRVFERV ANILHDDCAF LSAFGDVSKP ERYSGDNIIY KPPGHSAPDM VYLGAMTNFD VTYNWIQDKC VPLVREITFE NGEELTEEGLPFLILFHMKE DTESLEIFQN EVARQLISEK GTINFLHADC DKFRHPLLHI QKTPADCPVI AIDSFRHMYV FGDFKDVLIP GKLKQFVFDLHSGKLHREFH HGPDPTDTAP GEQAQDVASS PPESSFQKLA PSEYRYTLLR DRDEL
Molecular weight 48 kDa
Amino acids 30 to 406
Tags His tag N-Terminus
Additional sequence information ERP44 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 415 amino acids (30-406 a.a.) and having a molecular mass of 48 kDa. Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity > 90
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
Endoplasmic reticulum resident protein 44
Endoplasmic reticulum resident protein 44 kDa
Endoplasmic reticulum resident protein ERp44
Function Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
Sequence similarities Contains 1 thioredoxin domain.
Cellular localization Endoplasmic reticulum lumen.
Information by UniProt
References for Recombinant Human TXNDC4 protein (ab70117)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"