The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Monocyte protein 4
UBA6 ubiquitin activating enzyme E1
Ubiquitin activating enzyme 6
Ubiquitin activating enzyme E1 like 2
Ubiquitin activating enzyme E1 like protein 2
Ubiquitin like modifier activating enzyme 6
Ubiquitin-activating enzyme 6
Ubiquitin-activating enzyme E1-like protein 2
Ubiquitin-like modifier-activating enzyme 6
Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility.
Widely expressed. Isoform 2 is predominantly expressed in testis with higher expression in adult testis than in fetal testis.