Recombinant human UBE2J2 protein (ab188721)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      26 kDa including tags
    • Tags
      His tag N-Terminus
    • Additional sequence information
      The transmembrane and lumenal domains of this protein have been removed.

Specifications

Our Abpromise guarantee covers the use of ab188721 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    Typical enzyme concentration to support conjugation in vitro is 100 nM-1 µM depending on conditions.

  • Applications

    SDS-PAGE

    Functional Studies

  • Purity
    >95% by SDS-PAGE .

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.5
    Constituents: 0.03% DTT, 1.16% Sodium chloride, 1.19% HEPES

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • NCUBE-2
    • NCUBE2
    • Non-canonical ubiquitin-conjugating enzyme 2
    • PRO2121
    • UB2J2_HUMAN
    • UBC6
    • UBC6 homolog
    • ube2j2
    • Ubiquitin conjugating enzyme 6
    • Ubiquitin-conjugating enzyme E2 J2
    • Yeast UBC6 homolog
    see all
  • Function
    Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD).
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Belongs to the ubiquitin-conjugating enzyme family.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt

References

ab188721 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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