This product is an active protein and may elicit a biological response in vivo, handle with caution.
Chromosome 9 open reading frame 74
Ubiquitin related modifier 1
Ubiquitin related modifier 1 homolog
Ubiquitin-related modifier 1 homolog
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. May also act as an ubiquitin-like protein that is covalently conjugated to other proteins; the relevance of such function is however unclear in vivo.