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- SourceInsect cells
- Amino Acid Sequence
- Amino acids1 to 135
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Purity> 95
ab92591 is purified from auto-catalytic digestion of recombinant human urokinase produced in insect cells.
- Additional notes
The amino terminal fragment (ATF) contains the Kringle and Epidermal Growth Factor domains and is separated from LMW uPA by cleavage at the Lys135-Lys136 bond.
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Preparation and Storage
- Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.1M Sodium chloride, 0.1M HEPES, pH 7.4
- FunctionSpecifically cleave the zymogen plasminogen to form the active enzyme plasmin.
- Tissue specificityExpressed in the prostate gland and prostate cancers.
- Sequence similaritiesBelongs to the peptidase S1 family.
Contains 1 EGF-like domain.
Contains 1 kringle domain.
Contains 1 peptidase S1 domain.
modificationsPhosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.
- Cellular localizationSecreted.
Information by UniProt
Recombinant Human Urokinase protein images
References for Recombinant Human Urokinase protein (ab92591)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"