Recombinant Human Urokinase protein (ab92767)

Overview

Description

  • Nature
    Recombinant
  • Source
    Insect cells
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab92767 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    ab92767 is fully complexable with Human PAI-1.
  • Applications

    SDS-PAGE

    Functional Studies

  • Form
    Liquid
  • Additional notes
    Solubility: > 2 mg/mL ab92767 is fully complexable with Human PAI-1.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.1M Sodium chloride, 0.05M Sodium acetate, 1mM EDTA, pH 5.0

General Info

  • Alternative names
    • ATF
    • ATF uPA
    • BDPLT5
    • Plasminogen activator
    • Plasminogen activator urinary
    • Plasminogen activator urokinase
    • PLAU
    • QPD
    • u PA
    • U plasminogen activator
    • u-PA
    • U-plasminogen activator
    • uPA
    • URK
    • UROK_HUMAN
    • Urokinase plasminogen activator
    • Urokinase type plasminogen activator
    • Urokinase type plasminogen activator precursor
    • Urokinase-type plasminogen activator chain B
    see all
  • Function
    Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.
  • Tissue specificity
    Expressed in the prostate gland and prostate cancers.
  • Sequence similarities
    Belongs to the peptidase S1 family.
    Contains 1 EGF-like domain.
    Contains 1 kringle domain.
    Contains 1 peptidase S1 domain.
  • Post-translational
    modifications
    Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.
  • Cellular localization
    Secreted.
  • Information by UniProt

Images

  • 10% SDS-PAGE analysis of ab92767:
    Lane 1. 3ug ab92767 non reduced
    Lane 2. 3ug ab92767 + 12ug PAI-1 non reduced
    Lane 3. Prestained standard

References

ab92767 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

The urokinase protein ab92767 is amino acids 21 – 431. The numbering refers to to the UniProt record P00749. Here is a link to the page. http://www.uniprot.org/uniprot/P00749

And here is the amino acid sequence.

SNELHQVPSNCDCLNGGTCVSN...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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