Recombinant Human Urokinase protein (ab92767)

Overview

Description

  • NatureRecombinant
  • SourceInsect cells
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab92767 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityab92767 is fully complexable with Human PAI-1.
  • Applications

    SDS-PAGE

    Functional Studies

  • FormLiquid
  • Additional notesSolubility: > 2 mg/mL ab92767 is fully complexable with Human PAI-1.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.1M Sodium chloride, 0.05M Sodium acetate, 1mM EDTA, pH 5.0

General Info

  • Alternative names
    • ATF
    • ATF uPA
    • BDPLT5
    • Plasminogen activator
    • Plasminogen activator urinary
    • Plasminogen activator urokinase
    • PLAU
    • QPD
    • u PA
    • U plasminogen activator
    • u-PA
    • U-plasminogen activator
    • uPA
    • URK
    • UROK_HUMAN
    • Urokinase plasminogen activator
    • Urokinase type plasminogen activator
    • Urokinase type plasminogen activator precursor
    • Urokinase-type plasminogen activator chain B
    see all
  • FunctionSpecifically cleave the zymogen plasminogen to form the active enzyme plasmin.
  • Tissue specificityExpressed in the prostate gland and prostate cancers.
  • Sequence similaritiesBelongs to the peptidase S1 family.
    Contains 1 EGF-like domain.
    Contains 1 kringle domain.
    Contains 1 peptidase S1 domain.
  • Post-translational
    modifications
    Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.
  • Cellular localizationSecreted.
  • Information by UniProt

Recombinant Human Urokinase protein images

  • 10% SDS-PAGE analysis of ab92767:
    Lane 1. 3ug ab92767 non reduced
    Lane 2. 3ug ab92767 + 12ug PAI-1 non reduced
    Lane 3. Prestained standard

References for Recombinant Human Urokinase protein (ab92767)

ab92767 has not yet been referenced specifically in any publications.

Product Wall

The urokinase protein ab92767 is amino acids 21 – 431. The numbering refers to to the UniProt record P00749. Here is a link to the page. http://www.uniprot.org/uniprot/P00749

And here is the amino acid sequence.

SNELHQVPSNCDCLNGGTCVSN...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"