Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab82069 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    EMSA

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

General Info

  • Alternative names
    • bHLHb11
    • Class B basic helix-loop-helix protein 11
    • FCHL
    • FCHL 1
    • FCHL1
    • HGNC:12593
    • HYPLIP 1
    • HYPLIP1
    • Major late transcription factor
    • Major late transcription factor 1
    • MLTF
    • MLTF I
    • MLTFI
    • Transcription factor USF-1
    • UEF
    • Upstream stimulatory factor 1
    • Upstream transcription factor 1
    • Upstream transcription factor 1, isoform CRA_a
    • USF
    • USF 1
    see all
  • RelevanceUSF1 is a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E box motifs. USF1 has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this.
  • Cellular localizationNuclear

References for Recombinant Human USF1 protein (ab82069)

This product has been referenced in:
  • Terragni J  et al. The E-box Binding Factors Max/Mnt, MITF, and USF1 Act Coordinately with FoxO to Regulate Expression of Proapoptotic and Cell Cycle Control Genes by Phosphatidylinositol 3-Kinase/Akt/Glycogen Synthase Kinase 3 Signaling. J Biol Chem 286:36215-27 (2011). Read more (PubMed: 21873430) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab82069.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"