Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab82069 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    EMSA

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

General Info

  • Alternative names
    • bHLHb11
    • Class B basic helix-loop-helix protein 11
    • FCHL
    • FCHL 1
    • FCHL1
    • HGNC:12593
    • HYPLIP 1
    • HYPLIP1
    • Major late transcription factor
    • Major late transcription factor 1
    • MLTF
    • MLTF I
    • MLTFI
    • Transcription factor USF-1
    • UEF
    • Upstream stimulatory factor 1
    • Upstream transcription factor 1
    • Upstream transcription factor 1, isoform CRA_a
    • USF
    • USF 1
    see all
  • Relevance
    USF1 is a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E box motifs. USF1 has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this.
  • Cellular localization
    Nuclear

References

This product has been referenced in:
  • Terragni J  et al. The E-box Binding Factors Max/Mnt, MITF, and USF1 Act Coordinately with FoxO to Regulate Expression of Proapoptotic and Cell Cycle Control Genes by Phosphatidylinositol 3-Kinase/Akt/Glycogen Synthase Kinase 3 Signaling. J Biol Chem 286:36215-27 (2011). Read more (PubMed: 21873430) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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