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Source Escherichia coli
Amino Acid Sequence
Amino acids 25 to 698 Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity > 95
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Constituents: 50% Glycerol, PBS, pH 7.4
Function Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Tissue specificity Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
Sequence similarities Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
Domain Either the first or the fourth Ig-like C2-type domain is required for VLA4-dependent cell adhesion.
Post-translational modifications Sialoglycoprotein.
Cellular localization Membrane.
Information by UniProt
Recombinant Human VCAM1 protein images
SDS-PAGE - VCAM1 protein (His tag) (ab55238)
ab55238 on SDS-PAGE
References for Recombinant Human VCAM1 protein (ab55238)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"