The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityShows adipogenic effects in stimulated differentiating 3T3-L1 cells.
Endotoxin level< 0.100 Eu/µg
Shows adipogenic effects in stimulated differentiating 3T3-L1 cells.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
ReconstitutionReconstitute in distilled water
Pre B cell colony enhancing factor
Pre B cell colony enhancing factor 1
Pre B cell enhancing factor
Pre-B cell-enhancing factor
Pre-B-cell colony-enhancing factor 1
FunctionCatalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway.
Tissue specificityExpressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues.
PathwayCofactor biosynthesis; NAD(+) biosynthesis; nicotinamide D-ribonucleotide from 5-phospho-alpha-D-ribose 1-diphosphate and nicotinamide: step 1/1.
Sequence similaritiesBelongs to the NAPRTase family.
Dimer formation of recombinant PBEF (ab109137). Purified ab109137 was separated by SDS-PAGE and Western blot analysis was performed using rabbit anti-Nampt polyclonal antibody. In the absence of DTT ab109137 formed a homodimer, a homomultimer.
References for Recombinant Human Visfatin protein (ab109137)
has not yet been referenced specifically in any publications.
Publishing research using ab109137? Please let us know so that we can cite the reference in this datasheet.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"