The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
GalNAc-T-like protein 3
Polypeptide GalNAc transferase-like protein 3
Polypeptide N acetylgalactosaminyltransferase WBSCR17
pp GalNAc transferase 20
pp-GaNTase-like protein 3
Protein-UDP acetylgalactosaminyltransferase-like protein 3
Putative polypeptide N-acetylgalactosaminyltransferase-like protein 3
UDP GalNAc:polypeptide N acetylgalactosaminyltransferase like 3
UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 16
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3
Williams Beuren syndrome chromosome region 17
Williams-Beuren syndrome chromosomal region 17 protein
May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
Highly expressed in brain and heart. Weakly expressed in kidney, liver, lung and spleen.
Protein modification; protein glycosylation.
Involvement in disease
Note=WBSCR17 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. Contains 1 ricin B-type lectin domain.
There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding. The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.