Recombinant Human WDR68 protein (denatured) (ab111624)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant Human WDR68 protein (denatured)
See all WDR68 proteins and peptides -
Purity
> 90 % SDS-PAGE.
ab111624 was denatured using detergent during conventional chromatography purification process. -
Expression system
Escherichia coli -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MGSSHHHHHHSSGLVPRGSHMVYAMNWSVRPDKRFRLALGSFVEEYNNKV QLVGLDEESSEFICRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRV WRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTI WGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGA DGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEV VILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWD -
Predicted molecular weight
34 kDa -
Amino acids
19 to 295 -
Tags
His tag N-Terminus
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Description
Recombinant Human WDR68 protein
Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab111624 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 8.00
Constituents: 2.4% Urea, 0.02% DTT, 0.32% Tris HCl
General Info
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Alternative names
- AN11
- Dcaf7
- DCAF7_HUMAN
see all -
Function
Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. -
Pathway
Protein modification; protein ubiquitination. -
Sequence similarities
Belongs to the WD repeat DCAF7 family.
Contains 4 WD repeats. -
Cellular localization
Cytoplasm. Nucleus. Overexpression of DIAHP1 or active RHOA causes translocation from the nucleus to cytoplasm. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab111624 has not yet been referenced specifically in any publications.