Recombinant Human WDR68 protein (denatured) (ab111624)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionP61962
    • SpeciesHuman
    • SequenceMGSSHHHHHHSSGLVPRGSHMVYAMNWSVRPDKRFRLALGSFVEEYNNKV QLVGLDEESSEFICRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRV WRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTI WGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGA DGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEV VILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWD
    • Molecular weight34 kDa
    • Amino acids19 to 295
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab111624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 90 % SDS-PAGE.
    ab111624 was denatured using detergent during conventional chromatography purification process.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.02% DTT, 2.4% Urea

General Info

  • Alternative names
    • AN11
    • Dcaf7
    • DCAF7_HUMAN
    • DDB1- and CUL4-associated factor 7
    • HAN11
    • Human anthocyanin
    • Petunia
    • Seven WD repeat protein of the AN11 family 1
    • SWAN 1
    • WD repeat domain 68
    • WD repeat protein An11 homolog
    • WD repeat-containing protein 68
    • WD repeat-containing protein An11 homolog
    • WDR68
    see all
  • FunctionInvolved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesBelongs to the WD repeat DCAF7 family.
    Contains 4 WD repeats.
  • Cellular localizationCytoplasm. Nucleus. Overexpression of DIAHP1 or active RHOA causes translocation from the nucleus to cytoplasm.
  • Information by UniProt

Recombinant Human WDR68 protein (denatured) images

  • 15% SDS-PAGE showing ab111624 at approximately 33.6kDa (3µg).

References for Recombinant Human WDR68 protein (denatured) (ab111624)

ab111624 has not yet been referenced specifically in any publications.

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