Zinc binding alcohol dehydrogenase domain containing protein 1
Zinc-binding alcohol dehydrogenase domain-containing protein 1
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.
Belongs to the NADP-dependent oxidoreductase L4BD family.