The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Zinc finger DHHC domain-containing protein 15
Palmitoyltransferase specific for GAP43 and DLG4/PSD95.
Expressed in placenta, liver, lung, kidney, heart and brain.
Involvement in disease
Defects in ZDHHC15 are the cause of mental retardation X-linked type 91 (MRX91) [MIM:300577]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
Belongs to the DHHC palmitoyltransferase family. Contains 1 DHHC-type zinc finger.
The DHHC domain is required for palmitoyltransferase activity.