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Recombinant Human ZSWIM2 protein
Amino Acid Sequence
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
- E3 ubiquitin-protein ligase ZSWIM2
- MEKK1-related protein X
E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes.
Contains 2 RING-type zinc fingers.
Contains 1 SWIM-type zinc finger.
Contains 1 ZZ-type zinc finger.
The SWIM-type zinc finger is reqiered for ubiquitination activity.
Polyubiquitinated. Polyubiquitination is followed by degradation via the proteasome.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"