Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKD KLLCSQLQVADFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELK ATYREHVEAIKIGLTKALTQMEEAQRKRTQLREAFEQLQAKKQMAMEKRR AVQNQWQLQQEKHLQHLAEVSAEVRERKTGTQQELDGVFQKLGNLKQQAE QERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKPQQPTRPQEQS TGDTMGRDPGVSFKAVGLQPAGDVNLP
    • Amino acids
      1 to 277
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161309 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Human ZW10 interacting protein 1
    • HZwint 1
    • HZwint1
    • KNTC 2 AP
    • KNTC2AP
    • MGC 117174
    • MGC117174
    • ZW10 interacting kinetochore protein
    • ZW10 interacting protein 1
    • ZW10 interactor
    • ZW10 interactor, kinetochore protein
    • ZW10-interacting protein 1
    • ZWINT
    • ZWINT 1
    • Zwint-1
    • ZWINT_HUMAN
    • ZWINT1
    see all
  • Function
    Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.
  • Cellular localization
    Nucleus. Chromosome > centromere > kinetochore. Localizes to kinetochores from late prophase to anaphase.
  • Information by UniProt

Images

  • ab161309 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161309 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab161309.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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