Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionP35225
    • Molecular weight13 kDa

Specifications

Our Abpromise guarantee covers the use of ab119462 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityThe ED50 determined by the dose-dependent stimulation of the proliferation of TF-1 cells was < 1.0 ng/ml, corresponding to a specific activity of > 1 x 106 units/mg.
  • Applications

    Functional Studies

    SDS-PAGE

    HPLC

  • Purity> 98 % SDS-PAGE.
    >98% by SDS-PAGE and HPLC analysis Endotoxin level is <0.1 ng per µg of IL13.
  • FormLyophilised
  • Additional notesLyophilized ab119462 should be stored desiccated below 0°C
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Constituent: 0.073% Hydrochloric acid

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • ReconstitutionReconstitute in 5-10 mM HCl to a concentration of 0.1 µg/µl. The solution can then be diluted into other aqueous buffers.

General Info

  • Alternative names
    • Allergic rhinitis
    • ALRH
    • BHR1
    • Bronchial hyperresponsiveness 1 (bronchial asthma)
    • IL 13
    • IL-13
    • Il13
    • IL13_HUMAN
    • Interleukin 13
    • Interleukin-13
    • MGC116786
    • MGC116788
    • MGC116789
    • NC30
    • P600
    see all
  • FunctionCytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages.
  • Involvement in diseaseAllergic rhinitis
  • Sequence similaritiesBelongs to the IL-4/IL-13 family.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Recombinant IL13 protein (ab119462)

ab119462 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"