Recombinant Influenza A, H1N1 New Caledonia 20/99, Hemagglutinin protein (ab123221)

Overview

  • Product nameRecombinant Influenza A, H1N1 New Caledonia 20/99, Hemagglutinin protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • AccessionQ6WG00
    • Molecular weight72 kDa
    • Amino acids1 to 565

Specifications

Our Abpromise guarantee covers the use of ab123221 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

    HPLC

  • Endotoxin level= 0.100 Eu/µg
  • Purity> 90 % SDS-PAGE.
    Chromatographically purified. Purity checked by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain.
  • FormLiquid
  • Additional notesMay be stored at 4°C for short-term only. For long-term storage, add 0.1% HSA or BSA.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C.

    pH: 7.20
    Constituents: 0.14% Sodium phosphate, 0.88% Sodium chloride

General Info

  • Alternative names
    • HA
    • Hemagglutinin
    • Influenza A, H1N1 New Caledonia 20/99, Hemagglutinin
  • RelevanceBinds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore By similarity. RuleBase RU003324 SAAS SAAS001364.

References for Recombinant Influenza A, H1N1 New Caledonia 20/99, Hemagglutinin protein (ab123221)

ab123221 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"