This product is an active protein and may elicit a biological response in vivo, handle with caution.
EPH receptor B1
Eph tyrosine kinase 2
EPH-like kinase 6
Ephrin type B receptor 1
Ephrin type-B receptor 1
Neuronally-expressed EPH-related tyrosine kinase
soluble EPHB1 variant 1
Tyrosine protein kinase receptor EPH 2
Tyrosine-protein kinase receptor EPH-2
FunctionReceptor for members of the ephrin-B family. Binds to ephrin-B1, -B2 and -B3. Binding with the guidance cue ephrin-B2 at the optic chiasm midline redirect ventrotemporal (VT) retinal ganglion cells (RGCs) axons ipsilaterally. May be involved in cell-cell interactions in the nervous system.
Tissue specificityPreferentially expressed in brain.
Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. Contains 2 fibronectin type-III domains. Contains 1 protein kinase domain. Contains 1 SAM (sterile alpha motif) domain.