The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. Greater than 98% by SDS-PAGE and HPLC analysis
Additional notesThe reconstituted solution can be diluted into aqueous buffers and stored at –4°C for 1 week or –20°C for future use. For long-term storage it is recommended to add a carrier protein (0.1% HAS or BSA).
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 10mM Tris, pH 8.0
Endotoxin level is <0.1 ng per µg of IL15.
ReconstitutionReconstitute in water to a concentration of 0.1-1.0 µg/µl.
FunctionCytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha.
Tissue specificityMost abundant in placenta and skeletal muscle. It is also detected in the heart, lung, liver and kidney. IL15-S21AA is preferentially expressed in tissues such as testis and thymus.
Sequence similaritiesBelongs to the IL-15/IL-21 family.
Cellular localizationSecreted and Cytoplasm. Nucleus. IL15-S21AA is not secreted, but rather is stored intracellularly, appearing in the nucleus and cytoplasmic components.