Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Mouse
    • Sequence
      VSLRIQEGCSHLPSCCPSKEQEPPEEWLKWSSASVSPPEPLSHTHHAESC RASKDGPLNSRAISPWSYELDRDLNRVPQDLYHARCLCPHCVSLQTGSHM DPLGNSVPLYHNQTVFYRRPCHGEEGTHRRYCLERRLYRVSLACVCVRPR VMA
    • Molecular weight
      35 kDa
    • Amino acids
      17 to 169
    • Additional sequence information
      Recombinant mouse IL-17E is a non-glycosylated, disulfide-linked homodimer, containing 2x145 amino acid chains, with a total molecular weight of 35.5 kDa.

Specifications

Our Abpromise guarantee covers the use of ab117679 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    HPLC

  • Purity
    > 95 % SDS-PAGE.
    ab117679 was purified by proprietary chromatographic techniques and filter sterilized. Purity was determined to be greater than 95.0% as determined by RP-HPLC and by SDS-PAGE.
  • Form
    Lyophilised
  • Additional notes
    Lyophilized ab117679 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution, ab117679 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Please see notes section.

    Constituent: 99% Water

  • Reconstitution
    ab117679 was lyophilized from a concentrated (1 mg/ml) solution. It is recommended to reconstitute the lyophilized antibody in sterile ultra pure water, not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

General Info

  • Alternative names
    • IL 17E
    • IL 25
    • IL-17E
    • IL-25
    • IL17e
    • IL25
    • IL25_HUMAN
    • Interleukin 17E
    • Interleukin 25
    • Interleukin-17E
    • Interleukin-25
    • Interleukin17E
    • Interleukin25
    • OTTHUMP00000027946
    • OTTHUMP00000246238
    • UNQ3120/PRO10272
    see all
  • Function
    Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.
  • Tissue specificity
    Expressed at low levels in several tissues, including brain, kidney, lung, prostate, testis, spinal cord, adrenal gland, and trachea.
  • Sequence similarities
    Belongs to the IL-17 family.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab117679 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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