Recombinant mouse iNOS protein (ab58951)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesMouse

Specifications

Our Abpromise guarantee covers the use of ab58951 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activitySpecific Activity >7 units/mg protein.
  • Applications

    Functional Studies

  • FormLiquid
  • Additional notesThe enzyme loses approximately 10% of its activity after a single freeze-thaw cycle. During use, keep the solution on ice at all times.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Glycerol, 50mM HEPES, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • HEP-NOS
    • Hepatocyte NOS
    • HEPNOS
    • inducible
    • Inducible nitric oxide synthase
    • Inducible NO synthase
    • Inducible NOS
    • iNOS
    • MAC NOS
    • Macrophage NOS
    • Nitric oxide synthase
    • Nitric oxide synthase 2 inducible
    • Nitric oxide synthase 2 inducible macrophage
    • nitric oxide synthase 2A (inducible, hepatocytes)
    • Nitric oxide synthase inducible
    • nitric oxide synthase, macrophage
    • NOS
    • NOS 2
    • Nos II
    • NOS type II
    • nos2
    • NOS2_HUMAN
    • NOS2A
    • NOS2A, Inducible, Hepatocyte
    • Peptidyl-cysteine S-nitrosylase NOS2
    see all
  • FunctionProduces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
  • Tissue specificityExpressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets.
  • Sequence similaritiesBelongs to the NOS family.
    Contains 1 FAD-binding FR-type domain.
    Contains 1 flavodoxin-like domain.
  • Information by UniProt

References for Recombinant mouse iNOS protein (ab58951)

ab58951 has not yet been referenced specifically in any publications.

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