The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityUp to 2 µg/ ml LBP mediates binding of FITC-LPS (0.5µg/ml) to CD14+CHO transfectants (2 x 106/ml)
Additional notesThe lyophilized protein is best-stored desiccated below 0°C. Reconstituted mouse-LBP should be stored in working aliquots at -20°C. For long term storage it is recommended to add a carrier protein (10% BSA). Repeated freezing and thawing should be avoided
Up to 2 µg/ ml LBP mediates binding of FITC-LPS (0.5µg/ml) to CD14+CHO transfectants (2 x 106/ml)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Please see notes section.
pH: 7.20 Constituent: 99% PBS
ReconstitutionCentrifuge the vial prior to opening. Reconstitute in 10 µl of ultra-pure distilled H2O.
BPI fold containing family D, member 2
Lipopolysaccharide binding protein
LPS binding protein
FunctionBinds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with the CD14 receptor.
Sequence similaritiesBelongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.