Overview

Description

  • Nature
    Recombinant
  • Source
    CHO cells
  • Amino Acid Sequence
    • Accession
    • Species
      Mouse
    • Molecular weight
      64 kDa

Specifications

Our Abpromise guarantee covers the use of ab119732 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Up to 2 µg/ ml LBP mediates binding of FITC-LPS (0.5µg/ml) to CD14+CHO transfectants (2 x 106/ml)
  • Applications

    SDS-PAGE

    Functional Studies

  • Form
    Lyophilised
  • Additional notes
    The lyophilized protein is best-stored desiccated below 0°C. Reconstituted mouse-LBP should be stored in working aliquots at -20°C. For long term storage it is recommended to add a carrier protein (10% BSA). Repeated freezing and thawing should be avoided Up to 2 µg/ ml LBP mediates binding of FITC-LPS (0.5µg/ml) to CD14+CHO transfectants (2 x 106/ml)
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Please see notes section.

    pH: 7.20
    Constituent: 99% PBS

  • Reconstitution
    Centrifuge the vial prior to opening. Reconstitute in 10 µl of ultra-pure distilled H2O.

General Info

  • Alternative names
    • BPI fold containing family D, member 2
    • Bpifd2
    • LBP
    • LBP_HUMAN
    • LBP1
    • Lipopolysaccharide binding protein
    • Lipopolysaccharide-binding protein
    • LPS binding protein
    • Ly88
    • MGC22233
    • OTTHUMP00000030965
    • RP23-407H16.4
    see all
  • Function
    Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with the CD14 receptor.
  • Sequence similarities
    Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
  • Cellular localization
    Secreted.
  • Information by UniProt

Images

  • Natural LBP is a 58KD glycoprotein produced in liver. This recombinant Mouse LBP appears as a band of 64 kDa on SDS-PAGE.

References

ab119732 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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