The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. ab123757 is purified by proprietary chromatographic techniques. Purity is greater than 95% as determined by HPLC and SDS-PAGE.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20ºC.
pH: 7.40 Constituents: PBS, 0.02% Tween
ReconstitutionCentrifuge the vial prior to opening. Reconstitute in sterile H2O to a concentration of 100 µg/ml. This solution can then be diluted into other aqueous buffers
Cholinergic Differentiation Factor
Differentiation inducing factor
differentiation inhibitory activity
Differentiation stimulating factor
Hepatocyte stimulating factor III
Human interleukin in DA cells
Leukemia inhibitory factor
Melanoma derived LPL inhibitor
Melanoma-derived LPL inhibitor
FunctionLIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
Sequence similaritiesBelongs to the LIF/OSM family.