Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesMouse
    • SequenceRecombinant Murine MCP-5 is a 9.3 kDa protein containing 82 amino acid residues: GPDAVSTPVT CCYNVVKQKI HVRKLKSYRR ITSS QCPREA VIFRTILDKE ICADPKEKWVKNSINHLDKT SQTFILEPSC LG

Associated products

Specifications

Our Abpromise guarantee covers the use of ab9738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

    Neutralising

  • Endotoxin level< 0.100 Eu/µg
  • FormLyophilised
  • Additional notesThe biological activity of murine MCP-5 was determined by a chemotaxis assay using human peripheral blood monocytes. Significant chemotaxis was achieved using a concentration of 50 ng/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    n/a

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • C-C motif chemokine 12
    • Ccl12
    • CCL12_MOUSE
    • Macrophage/monocyte Chemotactic Protein
    • MCP-1-related chemokine
    • MCP-5
    • Monocyte chemoattractant protein 5
    • Monocyte chemotactic protein 5
    • OTTMUSP00000000792
    • Scya12
    • Small inducible cytokine A12
    • Small-inducible cytokine A12
    see all
  • FunctionChemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.
  • Tissue specificityPredominantly expressed in the lymph nodes and thymus. Also found in the salivary glands containing lymph nodes, breast, heart, lung, brain, small intestine, kidney and colon.
  • Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Recombinant mouse MCP5 protein (ab9738)

ab9738 has not yet been referenced specifically in any publications.

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