This product is an active protein and may elicit a biological response in vivo, handle with caution.
Mental retardation X linked 30
p21 (CDKN1A) activated kinase 3
p21 activated kinase 3
p21 CDKN1A activated kinase 3
P21 protein (Cdc42/Rac) activated kinase 3
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
Serine threonine protein kinase PAK 3
RelevancePAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. PAK3 forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. It may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. A point mutation in this gene has been linked to nonsyndromic X-linked mental retardation.
Recombinant mouse PAK3 protein images
Functional Studies - PAK3 protein (Tagged) (ab61414)
SDS-PAGE - PAK3 protein (Tagged) (ab61414)
References for Recombinant mouse PAK3 protein (ab61414)
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