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Source Baculovirus infected Sf9 cells
Amino Acid Sequence
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activity Specific Activity: 2127 pmol/min/µg.
Assay conditions: 10 mM Tris-HCl, pH7.4, 10 mM MgCl 2, 1 mM MnCl 2, 200 µM cAMP, 2.5 kU 5' nucleotidase, 37ºC, 20min.
Quantified by 5' nucleotidase cleaving the 5' AMP product and releasing the phosphate group which is detected by Malachite Green Reagent.
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped on Dry Ice. Store at -80°C.
Constituents: 20% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0
This product is an active protein and may elicit a biological response in vivo, handle with caution.
5''-cyclic phosphodiesterase 4C
cAMP specific 3' 5' cyclic phosphodiesterase 4C
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Tissue specificity Expressed in various tissues but not in cells of the immune system.
Pathway Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
Sequence similarities Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
Information by UniProt
Recombinant mouse PDE4C protein images
References for Recombinant mouse PDE4C protein (ab95475)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"