Recombinant mouse PDGF AA protein (ab78590)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesMouse
    • SequenceMSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATSNLN PDHREEETGR RRESGKNRKR KRLKPT

Specifications

Our Abpromise guarantee covers the use of ab78590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityBiological Activity: Determined by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells. The expected ED50 for this effect is 8-10 ng/ml.
  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    Purity Greater than 97% as determined by reducing and non-reducing SDS-PAGE, and by analytical HPLC. This product was sterile filtered.
  • FormLyophilised
  • Additional notesIt is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    None

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • ReconstitutionReconstitute the lyophilized product with sterile water at a concentration of 0.1 -0.5 mg's/ml, which can be further diluted into other aqueous solutions.

General Info

  • Alternative names
    • PDGF A
    • PDGF A chain
    • PDGF subunit A
    • PDGF-1
    • PDGF1
    • PDGFA
    • PDGFA_HUMAN
    • Platelet derived growth factor alpha chain
    • Platelet derived growth factor alpha isoform 2 preproprotein
    • Platelet derived growth factor alpha polypeptide
    • Platelet-derived growth factor A chain
    • Platelet-derived growth factor alpha polypeptide
    • Platelet-derived growth factor subunit A
    see all
  • FunctionPlatelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
  • Sequence similaritiesBelongs to the PDGF/VEGF growth factor family.
  • DomainThe long form contains a basic insert which acts as a cell retention signal.
  • Cellular localizationSecreted.
  • Information by UniProt

Recombinant mouse PDGF AA protein images

  • ab78590 used in Functional Studies.

References for Recombinant mouse PDGF AA protein (ab78590)

ab78590 has not yet been referenced specifically in any publications.

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