This product is an active protein and may elicit a biological response in vivo, handle with caution.
Kinase induced by depolarization
Pim 3 oncogene
Pim-3 proto-oncogene, serine/threonine kinase
Protein kinase Kid 1
Protein kinase Kid1
Serine/threonine kinase Pim 3
Serine/threonine kinase Pim3
Serine/threonine protein kinase Pim 3
Serine/threonine protein kinase Pim3
Serine/threonine-protein kinase Pim-3
FunctionAble to phosphorylate CDKN1B in vitro. Involved in cell cycle progression and suppression of apoptosis. Implicated in proliferation of human hepatoma cell lines.
Tissue specificityWidely expressed. No expression in colon, thymus, and small intestine. Expressed in human hepatoma cell lines but not in normal liver tissues. Expressed in colon cancer samples, particularly at the less advanced stages of cancer development.
Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. Contains 1 protein kinase domain.