Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Mouse

Associated products

Specifications

Our Abpromise guarantee covers the use of ab60891 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Purity
    > 95 % SDS-PAGE.
    Purity: >95% as determined by densitometry.
  • Form
    Liquid
  • Additional notes

    ab188554 (CaMKII peptide) can be utilized as a substrate for assessing Kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Calcium/calmodulin dependent protein kinase type 1B
    • Calcium/calmodulin-dependent protein kinase type 1B
    • CaM KI beta
    • CaM kinase I beta
    • CaM kinase IB
    • CaM-KI beta
    • CaMK1b
    • CaMKI beta
    • CaMKI-beta
    • EC 2.7.11.17
    • KCC1B_HUMAN
    • MGC45419
    • PNCK
    • Pregnancy up regulated non ubiquitously expressed CaM kinase
    • Pregnancy up-regulated non-ubiquitously-expressed CaM kinase
    see all
  • Function
    Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Phosphorylated by CAMKK1.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

Images

  • Sample Kinase Activity Plot.
  • ab60891 on SDS-PAGE, MW ~64 kDa.

References

ab60891 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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