Recombinant Mouse S100A9 protein (ab109951)



  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionP31725
    • SpeciesMouse
    • Molecular weight15 kDa including tags
    • Amino acids1 to 113
    • TagsHis tag N-Terminus


Our Abpromise guarantee covers the use of ab109951 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry


  • Mass spectrometry
  • Purity> 90 % SDS-PAGE.
    ab109951 was purified using conventional chromatography.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

General Info

  • Alternative names
    • Leukocyte L1 complex heavy chain
    • 60B8AG
    • CAGB
    • Calgranulin B
    • Calgranulin-B
    • Calprotectin L1H subunit
    • CFAG
    • CGLB
    • Cystic fibrosis antigen B
    • L1AG
    • Leukocyte L1 complex heavy chain
    • LIAG
    • MAC387
    • MIF
    • Migration inhibitory factor related protein 14
    • Migration inhibitory factor-related protein 14
    • MRP 14
    • MRP-14
    • MRP14
    • Myeloid-related protein 14
    • NIF
    • OTTHUMP00000015331
    • p14
    • Protein S100-A9
    • S100 A9
    • S100 calcium binding protein A9
    • S100 calcium binding protein A9 calgranulin B
    • S100 calcium-binding protein A9
    • S100A9
    • S10A9_HUMAN
    see all
  • FunctionCalcium-binding protein. Has antimicrobial activity towards bacteria and fungi. Important for resistance to invasion by pathogenic bacteria. Up-regulates transcription of genes that are under the control of NF-kappa-B. Plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS) (By similarity). Promotes tubulin polymerization when unphosphorylated. Promotes phagocyte migration and infiltration of granulocytes at sites of wounding. Plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1. Extracellular calprotectin binds to target cells and promotes apoptosis. Antimicrobial and proapoptotic activity is inhibited by zinc ions.
  • Tissue specificityExpressed by macrophages in acutely inflammed tissues and in chronic inflammation. Detected in peripheral blood leukocytes, in neutrophils and granulocytes. Detected at sites of vascular inflammation (at protein level). Also expressed in epithelial cells constitutively or induced during dermatoses.
  • Sequence similaritiesBelongs to the S-100 family.
    Contains 2 EF-hand domains.
  • Post-translational
    Phosphorylated. Phosphorylation inhibits activation of tubulin polymerization.
  • Cellular localizationSecreted. Cytoplasm. Cytoplasm > cytoskeleton. Cell membrane. Associates with tubulin filaments in activated monocytes. Targeted to the cell surface upon calcium influx. Released from blood leukocytes upon exposure to CSF2/GM-CSF, bacterial lipopolysaccharide (LPS) and during inflammatory processes. Serum levels are high in patients suffering from chronic inflammation.
  • Information by UniProt

Recombinant Mouse S100A9 protein images

  • 15% SDS-PAGE analysis of ab109951 (3µg)

References for Recombinant Mouse S100A9 protein (ab109951)

ab109951 has not yet been referenced specifically in any publications.

Product Wall

The laboratory tested the endotoxin level of ab109951, and it’s below (<) 1EU/ug.

We are sorry that we cannot be of more help on this occasion. We - the technical team - would like to wish you good luck with your research, and are always at your service, should you require further expert advice. Have a great weekend!

Thank you for your inquiry. My colleague is currently on tour for Abcam in Germany, but before she left she inquired about the endotoxin level of S100A9 protein ab109951. I was informed that, regrettably, the Endotoxin concentration of this prote...

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