The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityFully biologically active. Determined by its ability to chemoattract Human CCR9 transfected BaF3 Mouse pro-B cells using a concentration range of 0.1-0.5 ug/ml.
% SDS-PAGE. ab125179 is purified by proprietary chromatographic techniques. Purity is greater than 97.0% as determined by RP-HPLC and SDS-PAGE.
Additional notesab125179 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Store under desiccating conditions.
pH: 7.40 Constituent: 99% PBS
This product is an active protein and may elicit a biological response in vivo, handle with caution.
ReconstitutionIt is recommended to reconstitute the lyophilized TECK in sterile 18M?-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Upon reconstitution ab125179 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
C-C motif chemokine 25
Chemokine (C C motif) ligand 25
Chemokine (CC motif) ligand 25
Chemokine C C motif ligand 25
Chemokine CC motif ligand 25
Ck beta 15
Small inducible cytokine A25
Small inducible cytokine A25 isoform 1 precursor
Small inducible cytokine A25 isoform 2 precursor
Small inducible cytokine subfamily A (Cys Cys) member 25
Small inducible cytokine subfamily A Cys Cys member 25
Small inducible cytokine subfamily A, member 25
Small-inducible cytokine A25
Thymus expressed chemokine
FunctionPotentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1.
Tissue specificitySpecifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.