The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Measured by its binding ability in a functional ELISA. Immobilized Mouse GITR, His Tag at 10μg/mL (100 μL/well) can bind ab219721 with a linear range of 0.007-0.256 μg/mL.
< 1.000 Eu/µg
>95% by SDS-PAGE .
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.50 Constituents: 0.61% Tris buffer, 0.75% Glycine
Lyophilized from 0.22 µm filtered solution.
Note: 5-10% trehalose is commonly used for freeze drying, and after reconstitution, the trehalose is mostly about 3-5%.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
It is recommended to reconstitute the lyophilized protein in sterile deionized water to a final concentration of 1mg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage.
Activation inducible TNF related ligand
Activation-inducible TNF-related ligand
Glucocorticoid induced TNF related ligand
Glucocorticoid induced TNFR related protein ligand
Glucocorticoid-induced TNF-related ligand
Tumor necrosis factor (ligand) superfamily member 18
Tumor necrosis factor ligand 2A
Tumor necrosis factor ligand superfamily member 18
Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues.
Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.