The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityDetermined by the dose-dependent stimulation of MIP-2 production by Mouse spleen cells using a concentration range of 10-100 ng/ml.
Endotoxin level< 1.000 Eu/µg
% SDS-PAGE. Purity determined to be >95% by SDS PAGE and HPLC analysis
Determined by the dose-dependent stimulation of MIP-2 production by Mouse spleen cells using a concentration range of 10-100 ng/ml.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
Constituent: 99% PBS
This product is an active protein and may elicit a biological response in vivo, handle with caution.
ReconstitutionReconstitute with 0.5ml distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. It is recommended that the vial is gently mixed after reconstitution. Best use within 3 months from date of reconstitution.
Apo 2 ligand
Chemokine tumor necrosis factor ligand superfamily member 10
TNF Related Apoptosis Inducing Ligand
TNF related apoptosis inducing ligand TRAIL
TNF-related apoptosis-inducing ligand
Tumor necrosis factor (ligand) family member 10
Tumor Necrosis Factor (ligand) Superfamily Member 10
Tumor necrosis factor ligand superfamily member 10
FunctionCytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Tissue specificityWidespread; most predominant in spleen, lung and prostate.
Sequence similaritiesBelongs to the tumor necrosis factor family.